Poly A Specific Ribonuclease (PARN) Antibody

Catalogue No: abx002935
Price: £120.00
(Size: 20 µl)
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Poly A Specific Ribonuclease (PARN) Antibody Poly A Specific Ribonuclease (PARN) Antibody Poly A Specific Ribonuclease (PARN) Antibody

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PARN Antibody is a Rabbit Polyclonal antibody against PARN. The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target PARN
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PARN.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O95453 (UniProt, ExPASy)
UniProt Secondary AC B2RCB3, B4DDG8, B4DSB0, B4DWR4, B4E1H6
UniProt Entry Name PARN_HUMAN
Gene Symbol PARN
GeneID 5073
KEGG hsa:5073
String 9606.ENSP00000387911
Molecular Weight Calculated MW: 52 kDa, 66 kDa, 67 kDa, 73 kDa
Observed MW: 75 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Poly A Specific Ribonuclease (PARN) Antibody

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