Poly ADP Ribose Polymerase (PARP) Antibody
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Catalogue No: abx016081
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation.The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage.In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Research Articles on Poly ADP Ribose Polymerase (PARP)
| Target | Poly ADP Ribose Polymerase (PARP) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide of human PARP, conjugated to KLH. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P09874 (UniProt, ExPASy) |
| UniProt Secondary AC | B1ANJ4, Q8IUZ9 |
| UniProt Entry Name | PARP1_HUMAN |
| Gene Symbol | PARP1 |
| GeneID | 142 |
| OMIM | 173870 |
| HGNC | 270 |
| KEGG | hsa:142 |
| Ensembl | ENSG00000143799 |
| String | 9606.ENSP00000355759 |
| Molecular Weight | 117 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |