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Paired Box Protein Pax-3 (PAX3) Antibody
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Catalogue No: abx001407
Price:
£120.00
(Size: 20 µl)
Reviews: 
(1 Publications and Reviews)
(1 Publications and Reviews)
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PAX3 Antibody is a Rabbit Polyclonal antibody against PAX3. This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Research Articles on PAX3
| Target | PAX3 |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human PAX3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P23760 (UniProt, ExPASy) |
| UniProt Entry Name | PAX3_HUMAN |
| Gene Symbol | PAX3 |
| GeneID | 5077 |
| KEGG | hsa:5077 |
| String | 9606.ENSP00000375921 |
| Molecular Weight | Calculated MW: 22 kDa, 24 kDa, 44 kDa, 45 kDa, 52 kDa, 53 kDa, 55 kDa Observed MW: 65 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.58 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
