Menu

Paired Box Protein Pax-8 (PAX8) Antibody

Catalogue No: abx000957
Price: £120.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Available Options

* Size:




PAX8 Antibody is a Rabbit Polyclonal antibody against PAX8. PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX8 has 5 isoforms with calculated MW 31kd, 34kd, 41kd, 43kd and 48kd. And there is a 60kd band corresponding to the electrophoretic mobility of PAX8 (PMID:15650356). Proteintech’s 10336-1-AP antibody has cross-reactivities with the other PAX family members.

Target PAX8
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PAX8.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q06710 (UniProt, ExPASy)
UniProt Secondary AC Q09155, Q16337, Q16338, Q16339, Q4ZG35, Q96J49
UniProt Entry Name PAX8_HUMAN
Gene Symbol PAX8
GeneID 7849
KEGG hsa:784
String 9606.ENSP00000263334
Molecular Weight Calculated MW: 31 kDa, 34 kDa, 41 kDa, 43 kDa, 48 kDa
Observed MW: 48 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Paired Box Protein Pax-8 (PAX8) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)