Histone Acetyltransferase KAT2B (PCAF) Antibody

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Target	Histone Acetyltransferase KAT2B (PCAF)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 253-283 amino acids from the N-terminal region of human PCAF.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92831 (UniProt, ExPASy)
UniProt Secondary AC	Q6NSK1
UniProt Entry Name	KAT2B_HUMAN
KEGG	hsa:8850
String	9606.ENSP00000263754
Molecular Weight	Calculated MW: 93 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse KAT2B.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone Acetyltransferase KAT2B (PCAF)

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