Protocadherin Gamma-B1 (PCDHGB1) Antibody
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Catalogue No: abx030453
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Research Articles on Protocadherin Gamma-B1 (PCDHGB1)
| Target | Protocadherin Gamma-B1 (PCDHGB1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 773-799 amino acids from the C-terminal region of human PCDHGB1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9Y5G3 (UniProt, ExPASy) |
| UniProt Secondary AC | Q3SY75, Q9Y5C8 |
| UniProt Entry Name | PCDGD_HUMAN |
| Gene Symbol | PCDHGB1 |
| GeneID | 56104 |
| KEGG | hsa:56104 |
| String | 9606.ENSP00000429273 |
| Molecular Weight | Calculated MW: 100 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 0.27 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |