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Polycomb Group RING Finger Protein 2 (PCGF2) Antibody
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Catalogue No: abx028410
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Polycomb Group RING Finger Protein 2 (PCGF2) Antibody is a Rabbit polyclonal against Polycomb Group RING Finger Protein 2 (PCGF2). The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.
Research Articles on Polycomb Group RING Finger Protein 2 (PCGF2)
| Target | Polycomb Group RING Finger Protein 2 (PCGF2) |
| Research Area | Tumor Immunity |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 121-150 amino acids from the central region of Human Polycomb Group RING Finger Protein 2 (PCGF2). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35227 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NGD8 |
| UniProt Entry Name | PCGF2_HUMAN |
| Gene Symbol | PCGF2 |
| KEGG | hsa:7703 |
| String | 9606.ENSP00000482063 |
| Molecular Weight | Calculated MW: 37.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |