Phosphoenolpyruvate Carboxykinase, Cytosolic (PCK1) Antibody
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Catalogue No: abx033869
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. A mitochondrial isozyme of the encoded protein also has been characterized.
Research Articles on Phosphoenolpyruvate Carboxykinase, Cytosolic (PCK1)
| Target | Phosphoenolpyruvate Carboxykinase, Cytosolic (PCK1) |
| Research Area | Enzymes and Kinases, Metabolism, Endocrinology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 40-70 amino acids from the N-terminal region of human PCK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35558 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K437, B4DT64, Q8TCA3, Q9UJD2 |
| UniProt Entry Name | PCKGC_HUMAN |
| KEGG | hsa:5105 |
| String | 9606.ENSP00000319814 |
| Molecular Weight | Calculated MW: 69.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |