Phosphoenolpyruvate Carboxykinase, Cytosolic (PCK1) Antibody

PCK1 Antibody is a Rabbit Polyclonal antibody against PCK1. PCK1(Phosphoenolpyruvate carboxykinase, cytosolic) is also named as PEPCK1 and belongs to the phosphoenolpyruvate carboxykinase [GTP] family. It catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. It is also a main control point for the regulation of gluconeogenesis. In eukaryotes there are two isozymes: a cytoplasmic one and a mitochondrial one. Defects in PCK1 are the cause of cytosolic phosphoenolpyruvate carboxykinase deficiency (C-PEPCKD). This antibody is specific to PCK1.

Target	Phosphoenolpyruvate Carboxykinase, Cytosolic (PCK1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/400-600 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 490-622 of human PCK1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35558 (UniProt, ExPASy)
UniProt Secondary AC	A8K437, B4DT64, Q8TCA3, Q9UJD2
UniProt Entry Name	PCKGC_HUMAN
Gene Symbol	PCK1
GeneID	5105
NCBI Accession	NP_002582.3
KEGG	hsa:5105
String	9606.ENSP00000319814
Molecular Weight	Calculated MW: 69 kDa Observed MW: 69 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Phosphoenolpyruvate Carboxykinase, Cytosolic (PCK1)

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