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Proliferating Cell Nuclear Antigen (PCNA) Antibody
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Catalogue No: abx015958
Price:
US$427.75
(Size: 100 µl)
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The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta.The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication.In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.Two transcript variants encoding the same protein have been found for this gene.Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Research Articles on Proliferating Cell Nuclear Antigen (PCNA)
| Target | Proliferating Cell Nuclear Antigen (PCNA) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PCNA (AA: 53-196) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P12004 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R897, D3DW02 |
| UniProt Entry Name | PCNA_HUMAN |
| Gene Symbol | PCNA |
| GeneID | 5111 |
| OMIM | 176740 |
| HGNC | 8729 |
| KEGG | hsa:5111 |
| Ensembl | ENSG00000132646 |
| String | 9606.ENSP00000368458 |
| Molecular Weight | 28.7 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |