Proliferating Cell Nuclear Antigen (PCNA) Antibody

Catalogue No: abx000649
Price: £120.00
(Size: 20 µl)
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PCNA Antibody is a Rabbit Polyclonal antibody against PCNA. The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Target Proliferating Cell Nuclear Antigen (PCNA)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PCNA.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P12004 (UniProt, ExPASy)
UniProt Secondary AC B2R897, D3DW02
UniProt Entry Name PCNA_HUMAN
Gene Symbol PCNA
GeneID 5111
KEGG hsa:5111
String 9606.ENSP00000368458
Molecular Weight Calculated MW: 28 kDa
Observed MW: 35 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Proliferating Cell Nuclear Antigen (PCNA)

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