Proprotein Convertase Subtilisin/Kexin Type 2 (PCSK2) Antibody
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Catalogue No: abx033528
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US$326.25
(Size: 80 µl)
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Datasheet SDS
PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone.
Research Articles on Proprotein Convertase Subtilisin/Kexin Type 2 (PCSK2)
| Target | Proprotein Convertase Subtilisin/Kexin Type 2 (PCSK2) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 318-346 amino acids from the Central region of human PCSK2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P16519 (UniProt, ExPASy) |
| UniProt Entry Name | NEC2_HUMAN |
| KEGG | hsa:5126 |
| String | 9606.ENSP00000262545 |
| Molecular Weight | Calculated MW: 70.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow and Pig PCSK2. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |