Proprotein Convertase Subtilisin/Kexin Type 4 (PCSK4) Antibody
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Catalogue No: abx029128
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Proprotein convertases, including PCSK4, are calcium-dependent serine proteases related to bacterial subtilisins and to yeast kexin. These enzymes process precursor proteins to their active forms by selective cleavage of the polypeptide at sites following paired basic amino acids. In mammals, this family comprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM 600488), furin (FUR; MIM 136950), and PACE4 (MIM 167405). Substrates for these enzymes range from prohormones to precursors for growth factors to cell surface receptors and viral surface glycoproteins (Cao et al., 2001 [PubMed 11776387]).[supplied by OMIM].
Research Articles on Proprotein Convertase Subtilisin/Kexin Type 4 (PCSK4)
| Target | Proprotein Convertase Subtilisin/Kexin Type 4 (PCSK4) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 168-196 amino acids from the N-terminal region of human PCSK4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q6UW60 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8IY88, Q9UF79 |
| UniProt Entry Name | PCSK4_HUMAN |
| Gene Symbol | PCSK4 |
| KEGG | hsa:54760 |
| String | 9606.ENSP00000300954 |
| Molecular Weight | Calculated MW: 82.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |