Procalcitonin (PCT) Antibody

Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It is composed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine. Measurement of procalcitonin can be used as a marker of severe sepsis caused by bacteria and generally grades well with the degree of sepsis, although levels of procalcitonin in the blood are very low. PCT has the greatest sensitivity (85%) and specificity (91%) for differentiating patients with systemic inflammatory response syndrome (SIRS) from those with sepsis, when compared with IL-2, IL-6, IL-8, CRP and TNF-alpha. It is a biomarker of bacterial infection which may help gauge the severity and prognosis of patients with CAP. In addition to clinical predictors, PCT may assist in decisions pertaining to timing of discharge from hospital and the discontinuation of antibiotics.

PCT (Capture Antibody) is a Mouse Monoclonal antibody against Human PCT. It is recommended to use abx019247 (this product) as the capture antibody and abx019248 as the detection antibody.

Target	Procalcitonin (PCT)
Clonality	Monoclonal
Clone	X761
Reactivity	Human
Tested Applications	ELISA, WB, CLIA, TIA
Host	Mouse
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant PCT protein.
Isotype	IgG2b
Form	Liquid
Purity	> 95% (HPLC and SDS-PAGE)
Purification	Purified by Protein A or Protein G.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Gene Symbol	CALCA
Buffer	0.01 M PBS (pH 7.4) and 0.15 M NaCl. Does not contain preservatives.
Specificity	Specifically recognises human PCT.
Concentration	6.91 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Procalcitonin (PCT)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue