Programmed Cell Death Protein 10 (PDCD10) Antibody

PDCD10 Antibody is a Rabbit Polyclonal antibody against PDCD10. This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Target	Programmed Cell Death Protein 10 (PDCD10)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	ELISA
Host	Rabbit
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide of human PDCD10
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BUL8 (UniProt, ExPASy)
UniProt Secondary AC	A8K515, D3DNN5, O14811
UniProt Entry Name	PDC10_HUMAN
Gene Symbol	PDCD10
GeneID	11235
String	9606.ENSP00000376506
Molecular Weight	Calculated MW: 25 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Programmed Cell Death Protein 10 (PDCD10)

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