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Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B (PDE1B) Antibody
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Catalogue No: abx001714
Price:
£120.00
(Size: 20 µl)
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PDE1B Antibody is a Rabbit Polyclonal antibody against PDE1B. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
Research Articles on PDE1B
| Target | PDE1B |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human PDE1B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q01064 (UniProt, ExPASy) |
| UniProt Secondary AC | Q92825, Q96KP3 |
| Gene Symbol | PDE1B |
| GeneID | 5153 |
| Molecular Weight | Calculated MW: 59 kDa, 61 kDa Observed MW: 59 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
