Phosphodiesterase 4A, cAMP Specific (PDE4A) Antibody
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Catalogue No: abx029338
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed 8009369]).
Research Articles on Phosphodiesterase 4A, cAMP Specific (PDE4A)
| Target | Phosphodiesterase 4A, cAMP Specific (PDE4A) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human PDE4A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P27815 (UniProt, ExPASy) |
| UniProt Entry Name | PDE4A_HUMAN |
| Gene Symbol | PDE4A |
| KEGG | hsa:5141 |
| String | 9606.ENSP00000370078 |
| Molecular Weight | Calculated MW: 98.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |