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Platelet Derived Growth Factor Subunit B (PDGFB) Antibody

Catalogue No: abx001108
Price: £120.00
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Platelet Derived Growth Factor Subunit B (PDGFB) Antibody Platelet Derived Growth Factor Subunit B (PDGFB) Antibody Platelet Derived Growth Factor Subunit B (PDGFB) Antibody Platelet Derived Growth Factor Subunit B (PDGFB) Antibody

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PDGFB Antibody is a Rabbit Polyclonal antibody against PDGFB. The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Target PDGFB
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PDGFB.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01127 (UniProt, ExPASy)
UniProt Secondary AC G3XAG8, P78431, Q15354, Q6FHE7, Q9UF23
UniProt Entry Name PDGFB_HUMAN
Gene Symbol PDGFB
GeneID 5155
KEGG hsa:5155
String 9606.ENSP00000330382
Molecular Weight Calculated MW: 25 kDa, 27 kDa
Observed MW: 27 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Platelet Derived Growth Factor Subunit B (PDGFB) Antibody

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