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Platelet Derived Growth Factor Receptor Beta (PDGFRB) Antibody

Catalogue No: abx001792
Price: £120.00
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Platelet Derived Growth Factor Receptor Beta (PDGFRB) Antibody

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PDGFRB Antibody is a Rabbit Polyclonal antibody against PDGFRB. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Target Platelet Derived Growth Factor Receptor Beta (PDGFRB)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PDGFRB.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P09619 (UniProt, ExPASy)
UniProt Secondary AC B5A957, Q8N5L4
UniProt Entry Name PGFRB_HUMAN
Gene Symbol PDGFRB
GeneID 5159
KEGG hsa:5159
String 9606.ENSP00000261799
Molecular Weight Calculated MW: 37 kDa, 123 kDa
Observed MW: 182 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Platelet Derived Growth Factor Receptor Beta (PDGFRB) Antibody

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