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Platelet Derived Growth Factor Receptor Beta (PDGFRB) Antibody
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Catalogue No: abx001792
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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PDGFRB Antibody is a Rabbit Polyclonal antibody against PDGFRB. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Research Articles on Platelet Derived Growth Factor Receptor Beta (PDGFRB)
| Target | Platelet Derived Growth Factor Receptor Beta (PDGFRB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PDGFR beta |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P09619 (UniProt, ExPASy) |
| UniProt Secondary AC | B5A957, Q8N5L4 |
| UniProt Entry Name | PGFRB_HUMAN |
| Gene Symbol | PDGFRB |
| GeneID | 5159 |
| NCBI Accession | NP_002600.1 |
| KEGG | hsa:5159 |
| String | 9606.ENSP00000261799 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
