Protein Disulfide Isomerase A3 (PDIA3) Antibody

PDIA3 is the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

Target	Protein Disulfide Isomerase A3 (PDIA3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 446-475 amino acids from the C-terminal region of human PDIA3.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30101 (UniProt, ExPASy)
UniProt Secondary AC	Q13453, Q14255, Q8IYF8, Q9UMU7
UniProt Entry Name	PDIA3_HUMAN
KEGG	hsa:2923
String	9606.ENSP00000300289
Molecular Weight	Calculated MW: 56.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Disulfide Isomerase A3 (PDIA3)

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