Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1) Antibody

PDK1 Antibody is a Rabbit Polyclonal antibody against PDK1. PDK1(pyruvate dehydrogenase kinase isoform 1) is also named as PDHK1 and belongs to the PDK/BCKDK protein kinase family.It inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism(PMID:17683942).Starvation increases islet PDK activity(PMID:11723055).This antibody is speicfic to PDK1.

Target	Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 337-436 of human PDK1/PDHK1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15118 (UniProt, ExPASy)
UniProt Secondary AC	B2R6T1, B7Z937, D3DPD8, E9PD65, Q308M4
UniProt Entry Name	PDK1_HUMAN
Gene Symbol	PDK1
GeneID	5163
NCBI Accession	NP_002601.1
KEGG	hsa:5163
String	9606.ENSP00000376352
Molecular Weight	Calculated MW: 49 kDa Observed MW: 49 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Pyruvate Dehydrogenase Kinase Isozyme 1 (PDK1)

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