Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

PDX1 Antibody is a Rabbit Polyclonal antibody against PDX1. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Target	Pancreas/duodenum Homeobox Protein 1 (PDX1)
Clonality	Polyclonal
Reactivity	Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDX1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P52945 (UniProt, ExPASy)
UniProt Secondary AC	O60594, Q5VYW2
UniProt Entry Name	PDX1_HUMAN
Gene Symbol	PDX1
GeneID	3651
KEGG	hsa:3651
String	9606.ENSP00000370421
Molecular Weight	Calculated MW: 31 kDa Observed MW: 34 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Pancreas/duodenum Homeobox Protein 1 (PDX1)

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