Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

Catalogue No: abx002213
Price: £120.00
(Size: 20 µl)
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PDX1 Antibody is a Rabbit Polyclonal antibody against PDX1. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Target PDX1
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human PDX1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P52945 (UniProt, ExPASy)
UniProt Secondary AC O60594, Q5VYW2
UniProt Entry Name PDX1_HUMAN
Gene Symbol PDX1
GeneID 3651
KEGG hsa:3651
String 9606.ENSP00000370421
Molecular Weight Calculated MW: 30 kDa
Observed MW: 34 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on PDX1

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