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Retrotransposon-Derived Protein PEG10 (PEG10) Antibody

Catalogue No: abx002092
Price: £120.00
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Retrotransposon-Derived Protein PEG10 (PEG10) Antibody

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PEG10 Antibody is a Rabbit Polyclonal antibody against PEG10. This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.

Target PEG10
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PEG10.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q86TG7 (UniProt, ExPASy)
UniProt Secondary AC Q96A68, Q9UPV1
UniProt Entry Name PEG10_HUMAN
Gene Symbol PEG10
GeneID 23089
KEGG hsa:23089
String 9606.ENSP00000418944
Molecular Weight Calculated MW: 36 kDa, 80 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Retrotransposon-Derived Protein PEG10 (PEG10) Antibody

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