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Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A) Antibody
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Catalogue No: abx011860
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPAR gamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Research Articles on Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A)
| Target | Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARGC1A) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PGC-1alpha expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q9UBK2 (UniProt, ExPASy) |
| UniProt Entry Name | PRGC1_HUMAN |
| Gene Symbol | PPARGC1A |
| GeneID | 10891 |
| OMIM | 604517 |
| HGNC | 9237 |
| Ensembl | ENSG00000109819 |
| String | 9606.ENSP00000264867 |
| Molecular Weight | 91 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |