ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM) Antibody
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Catalogue No: abx004197
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US$217.50
(Size: 20 µl)
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Datasheet SDS
PFKM Antibody is a Rabbit Polyclonal antibody against PFKM. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Research Articles on ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM)
| Target | ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to PFKM. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P08237 (UniProt, ExPASy) |
| UniProt Secondary AC | J3KNX3, Q16814, Q16815, Q6ZTT1 |
| Gene Symbol | PFKM |
| GeneID | 5213 |
| NCBI Accession | NP_001160160.1 |
| Molecular Weight | Calculated MW: 85 kDa Observed MW: 85 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |