Pepsinogen C (PGC) Antibody

Catalogue No: abx002093
Price: £120.00
(Size: 20 µl)
Reviews: 2 reviews
(2 reviews)

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Pepsinogen C (PGC) Antibody

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Pepsinogen C Antibody is a Rabbit Polyclonal antibody against Pepsinogen C. This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

Target Pepsinogen C
Clonality Polyclonal
Reactivity Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human PGC.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P20142 (UniProt, ExPASy)
UniProt Secondary AC B4DVZ3, Q5T3D7, Q5T3D8
Gene Symbol PGC
GeneID 5225
Molecular Weight Calculated MW: 34 kDa, 42 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.69 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Pepsinogen C (PGC) Antibody

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