Pepsinogen C (PGC) Antibody
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Catalogue No: abx002093
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
Reviews: 
(2 Publications and Reviews)
(2 Publications and Reviews)
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Datasheet SDS
Pepsinogen C Antibody is a Rabbit Polyclonal antibody against Pepsinogen C. This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
Research Articles on Pepsinogen C (PGC)
| Target | Pepsinogen C (PGC) |
| Research Area | Enzymes and Kinases, Tumor Immunity, Gastroenterology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human Pepsinogen II |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P20142 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DVZ3, Q5T3D7, Q5T3D8 |
| Gene Symbol | PGC |
| GeneID | 5225 |
| NCBI Accession | NP_001159896.1 |
| Molecular Weight | Calculated MW: 34 kDa/42 kDa Observed MW: 45-50 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
