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Progesterone Receptor (PGR) Antibody
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Catalogue No: abx011382
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Progesterone receptor, a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. Although PRA and PRB share several structural domains, they are distinct transcription factors that mediate their own response genes and physiologic effects with little overlap.[
Research Articles on Progesterone Receptor (PGR)
| Target | Progesterone Receptor (PGR) |
| Research Area | Signal Transduction, Metabolism |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of PGR (aa731-909) expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P06401 (UniProt, ExPASy) |
| UniProt Secondary AC | A7LQ08, A7X8B0, B4E3T0, Q8TDS3, Q9UPF7 |
| UniProt Entry Name | PRGR_HUMAN |
| Gene Symbol | PGR |
| GeneID | 5241 |
| OMIM | 607311 |
| HGNC | 8910 |
| KEGG | hsa:5241 |
| Ensembl | ENSG00000082175 |
| String | 9606.ENSP00000325120 |
| Molecular Weight | 99 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |