Progesterone Receptor (PGR) Antibody

PGR: progesterone receptor.This gene encodes a member of the steroid receptor superfamily.The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B.The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap.The location of transcription initiation for isoform B has not been clearly determined.

Target	Progesterone Receptor (PGR)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of PGR (aa730-871) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P06401 (UniProt, ExPASy)
UniProt Secondary AC	A7LQ08, A7X8B0, B4E3T0, Q8TDS3, Q9UPF7
UniProt Entry Name	PRGR_HUMAN
Gene Symbol	PGR
GeneID	5241
OMIM	607311
HGNC	8910
KEGG	hsa:5241
Ensembl	ENSG00000082175
String	9606.ENSP00000325120
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Progesterone Receptor (PGR)

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