Protein Inhibitor of Activated STAT 1 (PIAS1) Antibody

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Catalogue No: abx026813
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintenance of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.

Target Protein Inhibitor of Activated STAT 1 (PIAS1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 607-637 amino acids from the C-terminal region of human PIAS1.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O75925 (UniProt, ExPASy)
UniProt Secondary AC B2RB67, B3KSY9, C5J4B4, Q147X4, Q99751, Q9UN02
UniProt Entry Name PIAS1_HUMAN
KEGG hsa:8554
String 9606.ENSP00000249636
Molecular Weight Calculated MW: 71.8 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Protein Inhibitor of Activated STAT 1 (PIAS1)


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