Particularly Interesting New Cys-His Protein 1 (PINCH) Antibody
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Catalogue No: abx011865
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading.
Research Articles on Particularly Interesting New Cys-His Protein 1 (PINCH)
| Target | Particularly Interesting New Cys-His Protein 1 (PINCH) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PINCH expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P48059 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RAJ4, B7Z483, B7Z7R3, B7Z907, Q53TE0, Q9BS44 |
| UniProt Entry Name | LIMS1_HUMAN |
| Gene Symbol | LIMS1 |
| GeneID | 3987 |
| OMIM | 602567 |
| HGNC | 6616 |
| KEGG | hsa:3987 |
| Ensembl | ENSG00000169756 |
| String | 9606.ENSP00000446121 |
| Molecular Weight | 37 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |





