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Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody

Catalogue No: abx002259
Price: £120.00
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Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody

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PIWIL4 Antibody is a Rabbit Polyclonal antibody against PIWIL4. PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.

Target PIWIL4
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human PIWIL4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q7Z3Z4 (UniProt, ExPASy)
UniProt Secondary AC B4DEG5, Q68CZ4, Q8N8G9, Q8N9V8, Q8NEH2
UniProt Entry Name PIWL4_HUMAN
Gene Symbol PIWIL4
GeneID 143689
KEGG hsa:143689
String 9606.ENSP00000299001
Molecular Weight Calculated MW: 52 kDa, 56 kDa, 96 kDa
Observed MW: 110 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody

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