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Pyruvate Kinase, Liver And RBC (PKLR) Antibody

Catalogue No: abx001571
Price: £120.00
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Pyruvate Kinase, Liver And RBC (PKLR) Antibody Pyruvate Kinase, Liver And RBC (PKLR) Antibody Pyruvate Kinase, Liver And RBC (PKLR) Antibody

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PKLR Antibody is a Rabbit Polyclonal antibody against PKLR. The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Target PKLR
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PKLR.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P30613 (UniProt, ExPASy)
UniProt Secondary AC O75758, P11973
UniProt Entry Name KPYR_HUMAN
Gene Symbol PKLR
GeneID 5313
KEGG hsa:5313
String 9606.ENSP00000339933
Molecular Weight Calculated MW: 58 kDa, 61 kDa
Observed MW: 64 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Pyruvate Kinase, Liver And RBC (PKLR) Antibody

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