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Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody

Catalogue No: abx001794
Price: £120.00
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Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody

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PLCG2 Antibody is a Rabbit Polyclonal antibody against PLCG2. The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Target PLCG2
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PLCG2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16885 (UniProt, ExPASy)
UniProt Secondary AC D3DUL3, Q3ZTS2, Q59H45, Q969T5
UniProt Entry Name PLCG2_HUMAN
Gene Symbol PLCG2
GeneID 5336
KEGG hsa:5336
String 9606.ENSP00000482457
Molecular Weight Calculated MW: 147 kDa
Observed MW: 175 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody

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