Plastin-3 (PLS3) Antibody

PLS3 Antibody is a Rabbit Polyclonal antibody against PLS3. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alternate splicing results in multiple transcript variants.

Target	Plastin-3 (PLS3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PLS3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P13797 (UniProt, ExPASy)
UniProt Secondary AC	A8K579, B1AQ09, B4DGB4, B7Z6M1, Q86YI6
UniProt Entry Name	PLST_HUMAN
Gene Symbol	PLS3
GeneID	5358
NCBI Accession	NP_005023.2
KEGG	hsa:5358
String	9606.ENSP00000348163
Molecular Weight	Calculated MW: 71 kDa Observed MW: 71 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Plastin-3 (PLS3)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue