Podocalyxin (PODXL) Antibody

This gene encodes a member of the sialomucin protein family.The encoded protein was originally identified as an important component of glomerular podocytes.Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane.Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. (provided by RefSeq)Tissue specificity: Glomerular epithelium cell (podocyte).

Target	Podocalyxin (PODXL)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human PODXL expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00592 (UniProt, ExPASy)
UniProt Secondary AC	A6NHX8, Q52LZ7, Q53ER6
UniProt Entry Name	PODXL_HUMAN
Gene Symbol	PODXL
GeneID	5420
OMIM	602632
HGNC	9171
KEGG	hsa:5420
Ensembl	ENSG00000128567
String	9606.ENSP00000367817
Molecular Weight	49 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Podocalyxin (PODXL)

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