Polymerase DNA Directed Gamma 2 (POLG2) Antibody

POLG2 Antibody is a Rabbit Polyclonal antibody against POLG2. This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Target	Polymerase DNA Directed Gamma 2 (POLG2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/10 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 216-485 of human POLG2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UHN1 (UniProt, ExPASy)
UniProt Secondary AC	O00419, Q0IJ81, Q96GW2, Q9UK35, Q9UK94
UniProt Entry Name	DPOG2_HUMAN
Gene Symbol	POLG2
GeneID	11232
NCBI Accession	NP_009146.2
String	9606.ENSP00000442563
Molecular Weight	Calculated MW: 55 kDa Observed MW: 55 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Polymerase DNA Directed Gamma 2 (POLG2)

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