RNA Polymerase II Subunit C (POLR2C) Antibody

POLR2C Antibody is a Rabbit Polyclonal antibody against POLR2C. This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21.

Target	RNA Polymerase II Subunit C (POLR2C)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human RPB3/POLR2C.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P19387 (UniProt, ExPASy)
UniProt Secondary AC	O15161
UniProt Entry Name	RPB3_HUMAN
Gene Symbol	POLR2C
GeneID	5432
NCBI Accession	NP_116558.1
KEGG	hsa:5432
String	9606.ENSP00000219252
Molecular Weight	Calculated MW: 31 kDa Observed MW: 38 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on RNA Polymerase II Subunit C (POLR2C)

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