DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

POLR2E Antibody is a Rabbit Polyclonal antibody against POLR2E. This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.

Target	DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/100 - 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human POLR2E.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P19388 (UniProt, ExPASy)
UniProt Secondary AC	B2R6L4, D6W5Y1, O43380, Q6PIH5, Q9BT06
UniProt Entry Name	RPAB1_HUMAN
Gene Symbol	POLR2E
GeneID	5434
NCBI Accession	NP_002686.2
KEGG	hsa:5434
String	9606.ENSP00000478303
Molecular Weight	Calculated MW: 25 kDa Observed MW: 26 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E)

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