Adrenocorticotropic Hormone (ACTH) Antibody

Catalogue No: abx002196
Price: £120.00
(Size: 20 µl)
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Adrenocorticotropic Hormone (ACTH) Antibody

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Adrenocorticotropic Hormone Antibody is a Rabbit Polyclonal antibody against Adrenocorticotropic Hormone. This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation.

Target Adrenocorticotropic Hormone (ACTH)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human POMC.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01189 (UniProt, ExPASy)
UniProt Secondary AC P78442, Q53T23, Q9UD39, Q9UD40
UniProt Entry Name COLI_HUMAN
Gene Symbol POMC
GeneID 5443
KEGG hsa:5443
String 9606.ENSP00000384092
Molecular Weight Calculated MW: 29 kDa
Observed MW: 29 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Adrenocorticotropic Hormone (ACTH) Antibody

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