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Adrenocorticotropic Hormone (ACTH) Antibody
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Catalogue No: abx002196
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US$348.00
(Size: 60 µl)
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Datasheet SDS
Adrenocorticotropic Hormone Antibody is a Rabbit Polyclonal antibody against Adrenocorticotropic Hormone. This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation.
Research Articles on Adrenocorticotropic Hormone (ACTH)
| Target | Adrenocorticotropic Hormone (ACTH) |
| Research Area | Neuroscience, Neuropeptides |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human POMC |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01189 (UniProt, ExPASy) |
| UniProt Secondary AC | P78442, Q53T23, Q9UD39, Q9UD40 |
| UniProt Entry Name | COLI_HUMAN |
| Gene Symbol | POMC |
| GeneID | 5443 |
| NCBI Accession | NP_000930.1 |
| KEGG | hsa:5443 |
| String | 9606.ENSP00000384092 |
| Molecular Weight | Calculated MW: 29 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
