POU Class 5 Homeobox 1 / OCT4 (POU5F1) Antibody
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Catalogue No: abx025342
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US$623.50
(Size: 100 µl)
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Datasheet SDS
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. This antibody is supplied as crude ascites.
Research Articles on POU Class 5 Homeobox 1 / OCT4 (POU5F1)
| Target | POU Class 5 Homeobox 1 / OCT4 (POU5F1) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/4000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human POU5F1 recombinant protein. |
| Isotype | IgM |
| Form | Liquid |
| Purification | Unpurified crude ascites. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q01860 (UniProt, ExPASy) |
| UniProt Entry Name | PO5F1_HUMAN |
| KEGG | hsa:5460 |
| String | 9606.ENSP00000259915 |
| Molecular Weight | Calculated MW: 38.6 kDa |
| Buffer | Ascites containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |