POU Class 6 Homeobox 2 (POU6F2) Antibody
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Catalogue No: abx026698
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Research Articles on POU Class 6 Homeobox 2 (POU6F2)
| Target | POU Class 6 Homeobox 2 (POU6F2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 34-61 amino acids from the N-terminal region of human POU6F2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P78424 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D1W2, C4AMB9, P78425, Q75ME8, Q86UM6, Q9UDS7 |
| UniProt Entry Name | PO6F2_HUMAN |
| NCBI Accession | NP_001159490.1 NP_009183.3 |
| KEGG | hsa:11281 |
| String | 9606.ENSP00000384004 |
| Molecular Weight | Calculated MW: 73.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |