Peroxisome Proliferator Activated Receptor Gamma (PPARG) Antibody

The protein encoded by this gene is a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR alpha, PPAR delta, and PPAR gamma. The protein encoded by this gene is PPAR gamma and is a regulator of adipocyte differentiation. Additionally, PPAR gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Multiple transcript variants that use alternate promoters and splicing have been identified for this gene. At least three of these variants encode the same isoform.

Target	Peroxisome Proliferator Activated Receptor Gamma (PPARG)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of PPARG (aa170-270) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P37231 (UniProt, ExPASy)
UniProt Entry Name	PPARG_HUMAN
Gene Symbol	PPARG
GeneID	5468
OMIM	137800
HGNC	9236
KEGG	hsa:5468
Ensembl	ENSG00000132170
String	9606.ENSP00000287820
Molecular Weight	58 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Peroxisome Proliferator Activated Receptor Gamma (PPARG)

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