Serine/threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit (PPP1CA) Antibody

Catalogue No: abx001796
Price: £120.00
(Size: 20 µl)
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Serine/threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit (PPP1CA) Antibody Serine/threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit (PPP1CA) Antibody

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PPP1CA Antibody is a Rabbit Polyclonal antibody against PPP1CA. The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target PPP1CA
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PPP1CA.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P62136 (UniProt, ExPASy)
UniProt Secondary AC A6NNR3, B2R908, P08129, P20653, P22802, Q07161
UniProt Entry Name PP1A_HUMAN
Gene Symbol PPP1CA
GeneID 5499
KEGG hsa:5499
String 9606.ENSP00000326031
Molecular Weight Calculated MW: 32 kDa, 37 kDa, 38 kDa
Observed MW: 38 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Serine/threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit (PPP1CA) Antibody

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