Serine/threonine-Protein Phosphatase PP1-Beta Catalytic Subunit (PPP1CB) Antibody

PPP1CB Antibody is a Rabbit Polyclonal antibody against PPP1CB. Protein phosphatase 1 (PP1) is the main eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular processes including protein-protein interactions, gene transcription, cell-cycle progression and apoptosis. It is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. The catalytic subunit of PP1 (PP1c) can interact with amount of regulatory subunits in vivo that target it to particular subcellular locations and regulate its activity towards specific substrates. PPP1CB migrated as a 37kd protein on SDS page.

Target	Serine/threonine-Protein Phosphatase PP1-Beta Catalytic Subunit (PPP1CB)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 227-327 of human PP1 beta.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P62140 (UniProt, ExPASy)
UniProt Secondary AC	B2R5V4, D6W565, P37140, Q5U087, Q6FG45
UniProt Entry Name	PP1B_HUMAN
Gene Symbol	PPP1CB
GeneID	5500
NCBI Accession	NP_002700.1
KEGG	hsa:5500
String	9606.ENSP00000378769
Molecular Weight	Calculated MW: 37 kDa Observed MW: 30-35 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serine/threonine-Protein Phosphatase PP1-Beta Catalytic Subunit (PPP1CB)

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