Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Antibody

PPP2R4 Antibody is a Rabbit Polyclonal antibody against PPP2R4. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	IF/ICC
Host	Rabbit
Recommended dilutions	IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human Ser/thr-PP2A activator (PTPA).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15257 (UniProt, ExPASy)
UniProt Entry Name	PTPA_HUMAN
Gene Symbol	PTPA
GeneID	5524
NCBI Accession	NP_821067.1
KEGG	hsa:5524
String	9606.ENSP00000377036
Molecular Weight	Calculated MW: 41 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4)

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