Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Antibody

Catalogue No: abx001563
Price: £120.00
(Size: 20 µl)
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PPP2R4 Antibody is a Rabbit Polyclonal antibody against PPP2R4. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target PPP2R4
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications IHC, IF/ICC
Host Rabbit
Recommended dilutions IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PPP2R4.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15257 (UniProt, ExPASy)
UniProt Entry Name PTPA_HUMAN
Gene Symbol PTPA
GeneID 5524
KEGG hsa:5524
String 9606.ENSP00000377036
Molecular Weight Calculated MW: 31 kDa, 33 kDa, 36 kDa, 40 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on PPP2R4

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