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Prolylcarboxypeptidase (PRCP) Antibody

Catalogue No: abx002965
Price: £120.00
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Prolylcarboxypeptidase (PRCP) Antibody

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PRCP Antibody is a Rabbit Polyclonal antibody against PRCP. The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Target PRCP
Clonality Polyclonal
Reactivity Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PRCP.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P42785 (UniProt, ExPASy)
UniProt Secondary AC A8MU24, B2R7B7, B3KRK5, B5BU34
UniProt Entry Name PCP_HUMAN
Gene Symbol PRCP
GeneID 5547
KEGG hsa:5547
String 9606.ENSP00000377055
Molecular Weight Calculated MW: 55 kDa, 58 kDa
Observed MW: 58 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Prolylcarboxypeptidase (PRCP) Antibody

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