PR Domain Zinc Finger Protein 2 (PRDM2) Antibody
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Catalogue No: abx026566
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US$326.25
(Size: 80 µl)
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Datasheet SDS
PRDM2 is a 250-kD nuclear protein containing 8 zinc finger motifs. It contains an RB-binding motif that is related to that of the adenovirus E1A oncoprotein; RIZ also shares an antigenic epitope with the C terminus of E1A. It is expressed in human retinoblastoma cells and at low levels in all other human cell lines examined. Using fluorescence in situ hybridization, the PRDM2 gene has been mapped to 1p36. PRDM2 may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, skin, and lymphoid tumors.
Research Articles on PR Domain Zinc Finger Protein 2 (PRDM2)
| Target | PR Domain Zinc Finger Protein 2 (PRDM2) |
| Clonality | Polyclonal |
| Reactivity | Rat |
| Tested Applications | ELISA, IHC |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/100 - 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant GST fusion protein encoding 245-573 AA of rat Riz1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q13029 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AJZ4, B5MC68, Q13149, Q14550, Q5THJ1, Q5VUL9 |
| UniProt Entry Name | PRDM2_HUMAN |
| NCBI Accession | NP_001007258.1 NP_001129082.1 NP_036363.2 NP_056950.2 |
| KEGG | hsa:7799 |
| String | 9606.ENSP00000235372 |
| Molecular Weight | Calculated MW: 188 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | This antibody also recognises the isoform beta (Riz2) of PRDM2 (185 kDa). |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |