Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3) Antibody

PRDX3 Antibody is a Rabbit Polyclonal antibody against PRDX3. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Target	Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-256 of human Peroxiredoxin 3 (PRDX3).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30048 (UniProt, ExPASy)
UniProt Entry Name	PRDX3_HUMAN
Gene Symbol	PRDX3
GeneID	10935
NCBI Accession	NP_006784.1
KEGG	hsa:10935
String	9606.ENSP00000298510
Molecular Weight	Calculated MW: 28 kDa Observed MW: 25 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Thioredoxin-Dependent Peroxide Reductase, Mitochondrial (PRDX3)

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