Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 1 Protein (PREX1) Antibody
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Catalogue No: abx026896
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3, 4, 5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Research Articles on Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 1 Protein (PREX1)
| Target | Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Rac Exchanger 1 Protein (PREX1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1134-1163 amino acids from the C-terminal region of human PREX1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q8TCU6 (UniProt, ExPASy) |
| UniProt Entry Name | PREX1_HUMAN |
| Gene Symbol | PREX1 |
| KEGG | hsa:57580 |
| String | 9606.ENSP00000361009 |
| Molecular Weight | Calculated MW: 186 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |